最新刊期
- 摘要：To address the instability, drifting at bends and rule violations in ship track control caused by the coexistence of complex flow fields and navigational rule constraints in inland tidal reaches, an adaptive track control method considering time-varying non-uniform flow fields and navigational rule constraints was proposed. A parameterized model of navigational environment elements was constructed to map environmental information to control variables; based on discrete tidal current data from charts, a spatio-temporally continuous flow field was reconstructed by an improved radial basis function (RBF) interpolation method. Based on ship kinematic and dynamic models considering flow-induced drift and relative flow velocity, flow field feedforward compensation was introduced to reduce the effects of cross-currents; a heading-error-based control strategy combining gain scheduling, integral anti-windup and derivative scheduling was designed to improve the control response in bends and under disturbances; navigational rule constraints such as speed limits in the bridge area were dynamically embedded by geo-fencing. Simulation experiments were conducted taking the waters near the Sutong Bridge as a case study. The results show that, with the flow field feedforward, the mean cross-track error (XTE) over the whole route is reduced from 25.32 m to 8.24 m, and the proposed method further reduces it to 5.37 m; in the speed-limited bridge section, the mean XTE is 2.03 m, lower than 19.35 m of the control group.关键词：digital twin;track control;time-varying flow field reconstruction;wind-current coupled dynamics;anti-windup control;navigational constraints1|0|0更新时间：2026-11-04
- 摘要：Malignant tumors are one of the major health problems facing humanity. Currently, there are many therapeutic methods besides surgery, such as immunotherapy and gene therapy. Isorhamnetin is a natural active ingredient derived from plants, which has been proven to possess anti⁃inflammatory, anti⁃tumor, and antioxidant properties. This article focuses on its anti⁃tumor effects and systematically elaborates on how isorhamnetin significantly inhibits tumor progression at the mechanistic level. It achieves this by regulating signaling pathways such as PI3K/AKT and MAPK, as well as through inducing cell apoptosis, arresting the cell cycle, and inhibiting the epithelial⁃mesenchymal transition process. Furthermore, studies have shown that isorhamnetin can synergize with some chemotherapeutic drugs to enhance therapeutic efficacy. However, its clinical application still faces numerous limitations, such as low water solubility and rapid metabolism in vivo, which remain key challenges to be addressed in future research.关键词：Isorhamnetin;Malignant Tumor;PI3K/AKT Pathway;MAPK Pathway;Apoptosis;Cell Cycle2|0|0更新时间：2026-11-03
- 摘要：ObjectiveTo investigate the effects of orthokeratology （Ortho⁃K） on choroidal structure and microcirculation in adolescents with low to moderate myopia and to analyze response differences based on myopia severity.MethodsThis prospective study enrolled 54 adolescents （aged 8⁃15 years） with low to moderate myopia. Participants were divided into a low myopia group （spherical equivalent [SE]: -0.50 D to -3.00 D, n=31） and a moderate myopia group （SE: -3.00 D to -6.00 D, n=23）. Axial length （AL） and macular choroidal parameters, including choroidal thickness (ChT) and the three⁃dimensional choroidal vascularity index (3D⁃CVI), were measured at baseline and after 1 week, 1 month, 3 months, 6 months, and 1 year of Ortho⁃K lens wear. ChT and 3D⁃CVI were assessed within nine macular sectors defined by concentric circles of 1 mm, 3 mm, and 6 mm diameter centered on the fovea. Intergroup differences were analyzed.ResultsThe increase in AL over time showed no significant difference between the two groups at any follow⁃up point （P>0.05）. Both groups exhibited a significant increase in ChT across all macular sectors and time points compared to baseline （P<0.001）. The magnitude of ChT increase was significantly greater in the moderate myopia group than in the low myopia group. The greatest increase in ChT occurred in the outer temporal （OT） sector for both groups, while the smallest increase occurred in the outer nasal （ON） sector. 3D⁃CVI significantly increased from baseline in all sectors and at all time points for both groups （P<0.001）. However, there was no significant difference in the magnitude of 3D⁃CVI increase between the two groups. The greatest increase in 3D⁃CVI occurred in the outer inferior （OI） sector for both groups, while the smallest increase occurred in the central foveal （C） sector.ConclusionOrthokeratology demonstrated comparable efficacy in controlling axial elongation and increasing 3D⁃CVI in adolescents with both low and moderate myopia. However, adolescents with moderate myopia exhibited a more pronounced increase in choroidal thickness compared to those with low myopia.关键词：myopia;Orthokeratology;Choroid;Swept⁃Source Optical Coherence Tomography Angiography （SS⁃OCTA）2|0|0更新时间：2026-11-03
- 摘要：ObjectiveTo assess the three‑dimensional accuracy and experience‑dependent compensatory effect of digital impressions in multidisciplinary dental treatments.MethodsAn evaluation system including accuracy (Root Mean Square Error, RMSE), expert‑novice operation time difference (skill gap, ΔT), and multidimensional subjective evaluation was established to compare impression efficacy in conventional orthodontic, periodontal, and single and double implant scenarios.ResultsThe overall RMSE of digital 3D‑printed models (0.076 9±0.019 5) mm was significantly lower than that of conventional plaster models (0.108 8±0.026 4) mm. In the orthodontic and periodontal groups, the skill gap ΔT was significantly reduced by 55.39% and 46.41%, respectively (P<0.01). In the double implant group, the variability of operation time decreased significantly. Multidimensional subjective evaluation showed better patient acceptance and convenience in the digital group (P<0.01), with clinicians preferring tiered digital workflows.ConclusionDigital impressions present higher 3D reconstruction accuracy and scenario‑specific experience compensation. They enhance clinical operational stability in orthodontic and periodontal treatments, but have a weaker compensatory effect in complex implant cases. These results provide a practical reference for clinical promotion, multidisciplinary division of labor, and task delegation management.关键词：Digital Impression;Experience Compensation;Clinical Efficacy;Three‑Dimensional Accuracy;Multidimentional Subjective Evaluation;Multidisciplinary Treatment2|0|0更新时间：2026-11-03
- 摘要：Mycotoxins are toxic secondary metabolites produced by fungal contamination of food, feed, and agricultural products, and their widespread co-occurrence in foods poses potential cumulative toxicity to human health. The integration of electrochemiluminescence (ECL) with paper chips provides a promising strategy for minimizing cross-reactivity and improving detection sensitivity compared with conventional lateral flow assays. In this study, an arrayed paper chip comprising nine independent detection units was fabricated by constructing ring-shaped carbon electrodes on chromatography paper coated with carbon ink. Ru@SiO2/N-GQDs composites were prepared by combining Ru@SiO2 with nitrogen-doped graphene quantum dots (N-GQDs) and subsequently conjugated with antibodies against aflatoxin B1 (AFB1), ochratoxin A (OTA), and fumonisin B1 (FB1), and then immobilized in separate detection units of the arrayed paper chip. By capturing ECL imaging signals using a smartphone, simultaneous detection of AFB1, OTA, and FB1 was achieved, with detection limits of 0.31 ng/mL, 0.32 ng/mL, and 0.49 ng/mL, respectively. This method was used for corn sample analysis, and good recoveries in the range of 96.0%-104.0% were obtained, demonstrating its potential for the on-site rapid analysis of multiple mycotoxins.关键词：electrochemiluminescence imaging;paper-based array;mycotoxin;biosensing;rapid detection9|4|0更新时间：2026-11-02
- 摘要：The (2+1)-dimensional Boiti-Leon-Pempinelli (BLP) equation is integrable and admits a wide class of coherent structures beyond classical solitons, but such structures are difficult to derive systematically. Combining the auxiliary equation mapping method with the homogeneous balance method, we obtain variable separation solutions that contain two arbitrary functions. These functions allow breather double solitons, symmetric breather solitons and double-period waves to be constructed within one scheme. Analysis of the associated potential field
- 摘要：Marine ranching environments often contain foreign objects such as abandoned nets, ropes, plastics, and metal components, which may not only interfere with the operation of aquaculture facilities but also affect the activity space of aquatic organisms and the local ecosystem. As different types of underwater targets require different treatment strategies, including removal, avoidance, or no action, existing underwater object detection and semantic segmentation methods mainly focus on learning semantic categories, while the corresponding actions are typically derived from predictions using predefined rules. Since action categories depend on semantic predictions, model training primarily emphasizes semantic recognition accuracy, making it difficult to explicitly constrain prediction errors that may lead to incorrect action decisions. To address this issue, we propose a semantic-action consistency based method for underwater foreign-object action map generation, which directly incorporates action prediction into model training. The model employs a semantic branch and an action branch to learn target categories and action categories, respectively, and exploits the correspondence between semantics and actions to enforce consistency between the two predictions, allowing semantic recognition to be jointly constrained by action prediction. Furthermore, a risk penalty loss is introduced to explicitly suppress high-risk errors in which regions requiring avoidance or no action are incorrectly predicted as removable. Experimental results show that the proposed method achieves Decision Accuracy values of 89.8% and 91.3% on the SeaClear and SUIM datasets, respectively, while reducing Critical Error to 4.3% and 3.9%. These results demonstrate the effectiveness of the proposed method in underwater foreign-object action map generation and high-risk error control.关键词：marine ranching;underwater foreign object recognition;action map generation;underwater image11|6|0更新时间：2026-10-28
- 摘要：ObjectiveTo explore the evaluation value of serum soluble intercellular adhesion molecule‑1 (sICAM‑1), Meteorin‑like protein (Metrnl), and the ratio of blood urea nitrogen to serum albumin (BAR) for the severity of diabetic ketoacidosis (DKA).MethodsA total of 101 DKA patients admitted to the General Hospital of Civil Aviation from July 2022 to July 2025 were selected as the DKA group, and 101 patients with simple type 2 diabetes mellitus (T2DM) and 101 healthy individuals undergoing physical check ups were respectively selected as the T2DM group and control (NC) group. The serum levels of sICAM‑1, Metrnl, and BAR in all study subjects were detected. Spearman correlation analysis was used to analyze the correlation between serum indicators and disease severity. Ordinal multivariate Logistic regression model was applied to screen the influencing factors of disease severity. ROC curve analysis was performed to evaluate the value of serum indicators in assessing severe DKA.ResultsCompared with the NC group, T2DM group, and DKA group, levels of FBG, HbA1c, serum sICAM‑1, and BAR were progressively higher, while Metrnl levels were progressively lower (P<0.05). Serum sICAM‑1 and BAR were gradually elevated with the aggravation of disease severity, and serum Metrnl was gradually decreased (P<0.05). Serum sICAM‑1 and BAR in DKA patients were positively correlated with the severity of the disease respectively (P<0.05), and serum Metrnl was negatively correlated with the severity of the disease (P<0.05). Serum sICAM‑1, BAR and Metrnl were all independent influencing factors for disease severity in DKA patients (P<0.05). The AUC value for the combined assessment of severe DKA using sICAM⁃1, Metrnl, and BAR was significantly greater than those for the single⁃marker assessments (Z=2.143, 2.274, and 2.165, respectively; P<0.05).ConclusionSerum sICAM‑1 and BAR were up‑regulated while Metrnl was down‑regulated in DKA patients, all of which exhibited good predictive efficacy for severe DKA.关键词：Diabetic Ketoacidosis;sICAM‑1;Metrnl;BAR;Severity of the Disease4|0|0更新时间：2026-10-28
- 摘要：Aiming at the problems of high residual stress and insufficient plasticity of UNSR30003 cobalt‑based elastic alloy ultra‑thin foils after large‑deformation cold rolling， the 0.1 mm ultra‑thin cold‑rolled foil with an accumulative deformation of 97.4% was taken as the research object. The regulation mechanisms of microstructures， mechanical properties and V‑spring elastic service response of alloy foils were investigated under three aging processes： low‑temperature single‑stage aging （450 ℃）， high‑temperature single‑stage aging （500 ℃）， and high‑low‑temperature two‑stage aging （450 ℃+750 ℃）. The results show that the cold‑rolled alloy exhibits submicron lamellar deformed microstructures， and shear bands penetrating multiple deformed grains are observed within the distorted matrix. The low‑temperature single‑stage aging at 450 ℃ achieves the peak strength （ultimate tensile strength of 2 820 MPa， hardness of 549.23HV） via fine dispersed precipitates and inherited dislocations， whereas the elongation after fracture decreases to 3.3%. The high‑temperature single‑stage aging at 500 ℃ promotes matrix recovery and precipitate coarsening， yielding a preliminary strength‑ductility balance. The two‑stage aging process of 450 ℃×300 min+750 ℃×80 min can effectively balance strength and ductility； an ultimate tensile strength of 1 600 MPa is maintained while the elongation after fracture increases to 6.7%， which is 19.64% and 103.03% higher than those of the cold‑rolled state and the low‑temperature single‑stage aged state， respectively. Moreover， its elastic modulus （205 GPa） and resistance to elastic deformation are superior to those of the cold‑rolled foil. Through hierarchical precipitation and stepwise stress‑release mechanisms， two‑stage aging induces substantial dislocation rearrangement and relieves residual stress， realizing the synergistic optimization of strength， ductility and elastic stiffness of the alloy foil. This work provides a reference for formulating heat‑treatment procedures of ultra‑thin precision elastic alloy components.关键词：UNS R30003 Cobalt-based Elastic Alloy;Ultra-thin Foil;Single‑and Two‑stage Aging;Microstructure;Strength-ductility Matching;Elastic Service Performance6|9|0更新时间：2026-10-28
- 摘要：Based on the ANSYS finite element platform， a three-dimensional thermal analysis model of multi-layer and multi-pass welding of a G115 steel small-diameter pipe （
- 摘要：The energy loss structure and energy supply–demand balance during the smelting process of a 100 t electric arc furnace （EAF） were quantitatively analyzed. Based on actual industrial production data， individual energy losses during the smelting process were quantitatively decomposed and analyzed， the evolution patterns of energy loss throughout the smelting cycle were systematically revealed， and a mathematical model for the electrical energy supply–demand balance of the EAF smelting process was established. The results show that each additional scrap charge increases the process energy loss by approximately 454.3 kWh. Heat dissipation through water-cooled components is the most significant energy loss pathway of the EAF， with the lost energy reaching 8 000 kWh-10 000 kWh， accounting for 13%-18% of the total energy. The sensible heat loss of flue gas and dust is significantly and positively correlated with the hot metal ratio： the higher the hot metal ratio， the greater the flue gas energy loss， which accounts for 5%-10% of the total energy. The high-temperature thermal radiation generated from the bath， electrodes， and arcs is primarily absorbed by the water-cooled furnace walls and roof， while the external thermal radiation loss is relatively low， accounting for approximately 1.1%. The chemical heat of different scrap types is approximately 50.0 kWh/t； due to variations in slag carryover， volatile matter， and impurity content， the overall energy demand of scrap ranges from 351.5 to 424.8 kWh/t. Based on the staged energy loss characteristics and the energy supply-demand balance， the established model yields a proportion of 95.05% for data with calculation deviations within ±10 kWh/t， with an overall model error of less than 3%. The research findings provide a reliable theoretical basis and data support for intelligent optimization of the EAF power supply curve and for energy saving and consumption reduction.关键词：EAF;Energy loss;Water Cooling;Supply-demand Balance10|7|0更新时间：2026-10-28
- 摘要：This study focuses on FGH4097 superalloy revert scrap. Based on a 2 t vacuum horizontal continuous casting facility， high-purity melting experiments were conducted with bottom-blowing argon. The entire process of argon bubble rising， crossing the melt pool interface， and bursting was recorded by high-temperature in-situ visual observation. By combining finite-difference numerical simulations of the heat conduction equation， the disturbance patterns of the temperature and viscosity fields caused by the bubbles and their influence on inclusion removal were systematically investigated. Experimental results show that melt temperature is the key factor governing bubble interfacial crossing behavior. In the range of 1 550 ℃–1 500 ℃， bubbles struggle to break through the top interface due to insufficient surface tension， leading to limited flotation purification efficiency. When the temperature drops below 1 500 ℃， a pronounced heat-affected zone forms around the bubbles， increasing the local melt viscosity， which enhances the adhesion and capture of fine inclusions. Bubbles can then stably carry inclusions across the interface and burst under vacuum， after which the inclusions are adsorbed by slag or crucible walls for removal. Numerical simulation results indicate that upon entering the melt， the bubble interior and its surrounding region maintain a significantly lower temperature than the bulk melt for several seconds， thereby forming a radial temperature gradient， with a corresponding localized increase in viscosity， which agrees well with experimental observations. The study reveals that inclusion removal by bubble flotation follows a triple coupling mechanism： thermal adhesion， interfacial adsorption， and mechanical entrapment. It clarifies the purification mechanism under the synergistic effect of temperature field， viscosity field， and bubble behavior. The findings provide a theoretical basis and process guidance for temperature range selection， argon blowing parameter optimization， and high-purity recycling of superalloy revert scrap in vacuum horizontal continuous casting.关键词：Superalloy;Vacuum Horizontal Continuous Casting;Bottom-Blowing Argon;Bubble Dynamics;Inclusion Removal;Numerical Simulation of Heat Conduction8|6|0更新时间：2026-10-28
- 摘要：High-strength valve spring steel has exceptionally high requirements for fatigue performance and service reliability， and non-metallic inclusions in steel are a key factor affecting its overall performance. The effects of Cs2O on the physicochemical properties of CaO-SiO2-Al2O3-MgO refining slag and the cleanliness of molten steel were systematically studied with 65Si2CrV high-strength valve spring steel as the research object and the mechanism of action was revealed by combining the changes in viscosity and surface tension of refining slag. The results show that Cs2O， as a typical network modifier， can produce free oxygen ions （O2-） at high temperatures by ionization， which can promote the depolymerization of silicate network structure， and transform the high degree of polymerization structural units （Q2， Q3） into low degree of polymerization units （Q0， Q1）. It causes the decrease in the viscosity and surface tension of refining slag， thereby improving the fluidity of slag and the wettability of slag-steel interface.With the addition of 5% w［Cs2O］ to the refining slag， the cleanliness of the molten steel is significantly improved. The total oxygen mass fractions of the two steels are 0.004 0% and 0.002 3%， respectively， representing a reduction of 42.5% for the latter compared with the former； the numbers of inclusions per unit area are 40/mm2 and 16/mm2， respectively， corresponding to a decrease of 60% in the latter compared with the former. At the same time， the average composition point of inclusions migrates to the low-melting-point region at 1 400 ℃， the large-size brittle inclusions are effectively controlled， and the inclusion removal efficiency is significantly improved. This study provides theoretical guidance for the design of new alkali metal oxide refining slag and the production of high-cleanliness valve spring steel.关键词：Valve Spring Steel;Cs2O;Refining Slag;Inclusions;Molten Steel Cleanliness8|8|0更新时间：2026-10-28
- 摘要：Ladle bottom-blowing argon refining is essential for removing non-metallic inclusions from molten steel and improving steel cleanliness. However， in actual production， a size-selective issue still exists： inclusions larger than 150 μm can be removed quite effectively， while a portion of fine particles smaller than 50 μm always remains. To investigate this problem， 3D ladle model was built using the VOF-DPM coupled method and a size-grouped capture probability model was implemented. By referring to bubble-particle interaction theory， a scaling law that links the effective attachment factor to particle size was derived and incorporated into Fluent via UDFs. This allowed the capture behavior of six particle groups （50 μm to 300 μm） to be judged differently. The simulation shows that both bubble capture and surface retention control the removal efficiency， but their dominance varies significantly with particle size. For 50 μm particles， the bubble capture rate is 39.0% by theend of the simulation， and the surface capture rate is 44.02%； if the time is extrapolated to 2 h， the overall removal rate would reach 72.93%. For particles ≥200 μm， the removal is mainly attributed to surface retention after flotation， which accounts for over 60% of the removal， and the overall removal rate levels off within the 150 μm–200 μm size range， reaching 82.1% at 200 μm. It was also found that the inability to remain stably at the surface is the main reason why fine particles are difficult to remove： 50 μm particles can only stay at the surface for about 49.3 s on average， while particles ≥150 μm can remain for over 578 s. These results clearly reveal the transition of capture mechanisms with particle size， and they are considered to be of practical reference value for the precise adjustment of the bottom-blowing argon refining process.关键词：Bottom-Blowing Argon;Ladle;Inclusion Removal;VOF-DPM Coupled Method;Particle Size-grouped Capture5|4|0更新时间：2026-10-28
- 摘要：Ultra-high strength structural steel is widely used in heavy equipment fields， and the synergistic matching of its strength and low-temperature toughness is a research focus. The conventional offline quenching and tempering （RQ-T） process has issues such as long processing cycles and microstructural coarsening. In this study， the direct quenching and tempering （DQ-T） process was adopted to synergistically improve strength and toughness through microstructural refinement. The microstructure and fine structure of Q1300E steel plates subjected to DQ-T and RQ-T processes were comparatively investigated by optical microscopy （OM）， transmission electron microscopy （TEM）， and electron backscatter diffraction （EBSD）. Room-temperature tensile tests and Charpy impact tests at -40 °C were also conducted. The results show that the direct quenching and tempering at 190 °C process exhibits the best performance， with a yield strength reaching 1 435 MPa and an impact energy of 52.5 J at -40 °C. Compared with the RQ-T process， the DQ-T process refines the lath substructure， increases the dislocation density， enhances hardenability， and simultaneously obtains more retained austenite， which effectively improves low-temperature toughness， thereby synergistically enhancing both strength and impact energy at -40 °C.关键词：Ultra-high Strength Structural Steel;Online Quenching Process;Hardenability;Lath Substructure;Strength and Toughness12|5|0更新时间：2026-10-28
- 摘要：In this work, we establish a version of the global bifurcation theorem for nonlinear Sturm-Liouville problem
- 摘要：ObjectiveTo explore the role of intestinal butyrate metabolism in liver ischemia⁃reperfusion injury (IRI) and its molecular mechanism.MethodsA mouse model of IRI was established by 70% liver ischemia. A butyrate⁃producing bacteria⁃deficient model was established by streptomycin treatment. Exogenous butyrate supplementation was used for intervention. Serum enzymes, pathology, apoptosis, inflammation and mitochondrial ultrastructure were detected in different models. The changes of histone deacetylase 3 （HDAC3)/NF⁃κB pathway were verified by transcriptome sequencing and Western Blot.ResultsStreptomycin treatment aggravated IRI in mice, with significantly increased ALT and AST levels, more extensive confluent necrosis, disrupted hepatic cords and severe inflammatory cell infiltration in the liver, increased apoptosis, and aggravated mitochondrial cristae disintegration and vacuolization. Exogenous butyrate supplementation significantly reversed the above pathological phenotypes. Mechanistically, butyrate inhibited HDAC3 activity, stabilized IκBα, blocked NF⁃κB p65 nuclear translocation and the release of downstream inflammatory factors.ConclusionThe absence of intestinal butyrate⁃producing bacteria increases the susceptibility to IRI. Butyrate exerts anti⁃inflammatory and mitochondrial protective effects by inhibiting the HDAC3/NF⁃κB pathway. Restoring the intestinal butyrate⁃producing bacteria niche or supplementing butyrate during the perioperative period may become a new strategy to alleviate liver IRI.关键词：Butyrate;Hepatic Ischemia⁃Reperfusion Injury;Liver Transplantation;HDAC3;NF⁃κB2|1|0更新时间：2026-10-26
- 摘要：博斯腾湖为我国最大内陆淡水湖，其渔业发展历经土著鱼类捕捞、经济鱼类引种移植到生态修复的转型阶段。长期的引种移植导致渔获物优势种发生2次重大更替，湖泊鱼类群落小型化问题曾较为突出。自 2014 年起，通过生态输水、污染治理、增殖放流等综合整治措施，湖泊生态环境显著改善，扁吻鱼（Aspiorhynchus laticeps）等土著鱼类种群逐步恢复，但受经济鱼类自然增殖滞后的影响，总产量仍持续偏低。本文系统梳理博斯腾湖渔业60余年发展历程，剖析当前发展瓶颈；借鉴千岛湖保水渔业、长寿湖富硒品牌建设等案例，提出优化鱼类群落结构、提升增殖效率、强化品牌建设、完善监测体系、推动渔文旅融合等对策，为西北干旱区内陆湖泊生态渔业高质量发展提供实践范本与参考。关键词：博斯腾湖;渔业资源;扁吻鱼;种群演替;增殖放流;生态渔业1|2|0更新时间：2026-10-23
- 摘要：山东省菏泽市牡丹区肉羊全舍饲养殖转型中存在成本高、技术弱、效益不稳等难题，需要构建适配本地的节本增效技术体系与推广路径。本文在分析当地肉羊产业现状与制约短板的基础上，系统阐述了饲料高效利用、TMR精准营养、高效繁育及分阶段育肥等核心技术，剖析了在认知、设施及服务层面的推广制约因素，提出了“项目驱动－建设示范场－基层培训赋能”的推广应用路径，并对实践案例和应用效益进行分析，通过协同实施节本增效技术，可在保障肉羊健康的前提下，提升饲料与繁殖效率，为当地肉羊北产业升级提供实践参考。关键词：肉羊;全舍饲;TMR日粮;节本增效;高效繁育;精准育肥1|1|0更新时间：2026-10-23
- 摘要：2026年5月，玉溪市红塔区某养殖场饲养的铁脚麻肉鸡出现排鲜红色或棕褐色粪便、咳嗽、打喷嚏等症状。畜主先后2次自行用药治疗后，病情未能得到有效控制，反而持续加重，病死鸡数量逐日增多。病理剖检显示，病死鸡鼻腔黏膜充血、气管黏膜出血，气管内有块状或条状黄色干酪样分泌物，盲肠内充满血液或血凝块。分别采集病死鸡的新鲜粪便、喉气管、肺脏组织样品，采用饱和盐水浮聚法进行寄生虫检测，并应用RT-PCR技术开展病毒检测。检测结果显示，鸡粪便中检出球虫虫卵；喉气管、肺脏组织检测H9N2亚型禽流感病毒呈阳性，鸡传染性支气管炎和传染性喉气管炎病毒检测均呈阴性。结合该病例的临床症状、病理变化及流行病学调查，确诊为盲肠球虫病与H9N2亚型禽流感混合感染。采取药物治疗及综合防治措施后，发病鸡群恢复了健康，该病例未造成水平传播。关键词：铁脚麻肉鸡;球虫病;禽流感;混合感染;诊治;生物安全1|1|0更新时间：2026-10-23
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