1.武汉科技大学附属华润武钢总医院内分泌科 湖北 武汉 430080
2.武汉科技大学医学部医学院 湖北 武汉 430065
唐焕珺,女,2001—,医学硕士生,主要从事内分泌与代谢相关疾病的研究,E⁃mail:2469710483@qq.com。
林萱,E⁃mail:854964946@qq.com。
收稿:2026-03-25,
网络首发:2026-10-16,
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唐焕珺, 林萱. 代谢功能障碍相关脂肪性肝病的最新研究进展[J/OL]. 武汉大学学报(医学版), 2026,1-7.
TANG Huanjun, LIN Xuan. Recent research advances in metabolic dysfunction⁃associated steatotic liver disease[J/OL]. Medical Journal of Wuhan University, 2026, 1-7.
唐焕珺, 林萱. 代谢功能障碍相关脂肪性肝病的最新研究进展[J/OL]. 武汉大学学报(医学版), 2026,1-7. DOI: 10.14188/j.1671-8852.2026.0485.
TANG Huanjun, LIN Xuan. Recent research advances in metabolic dysfunction⁃associated steatotic liver disease[J/OL]. Medical Journal of Wuhan University, 2026, 1-7. DOI: 10.14188/j.1671-8852.2026.0485.
肥胖在世界范围内流行,代谢功能障碍相关脂肪性肝病(MASLD)的患病率也在稳步升高,为我国带来了严重的经济与疾病负担,现有的治疗主要通过生活方式的改变来缓解肝脏脂肪变性的程度。MASLD的发病机制复杂,目前治疗方案包括生活方式干预、药物治疗、手术治疗等,本文重点围绕MASLD发病机制及治疗手段来阐述其最近研究进展。
Obesity has reached epidemic proportions worldwide
and the prevalence of metabolic dysfunction⁃associated steatotic liver disease (MASLD) is steadily increasing
imposing a substantial economic and disease burden on China. Current treatments mainly rely on lifestyle modifications to alleviate hepatic steatosis. The pathogenesis of MASLD is complex
and existing therapeutic strategies include lifestyle intervention
pharmacotherapy
and surgical treatment. This review focuses on the recent research advances in the pathogenesis and therapeutic approaches of MASLD.
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