1.湖北医药学院附属随州医院皮肤科 湖北 随州 441300
2.武汉大学人民医院皮肤科 湖北 武汉 430060
汪方玲,女,1986—,医学硕士,主治医师,主要从事皮肤科治疗等方面研究,E⁃mail:492338944@qq.com
刘随,男,1974—,医学硕士,主任医师,主要从事皮肤病治疗等方面研究,E⁃mail:1060187751@qq.com
收稿:2024-10-30,
纸质出版:2025-07-25
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汪方玲,刘随,沈艳等.医用臭氧水治疗淤积性皮炎的临床疗效[J].武汉大学学报(医学版),2025,46(07):911-915.
WANG Fangling,LIU Sui,SHEN Yan,et al.Clinical therapeutic effect of medical ozonated water on stasis dermatitis[J].Medical Journal of Wuhan University,2025,46(07):911-915.
汪方玲,刘随,沈艳等.医用臭氧水治疗淤积性皮炎的临床疗效[J].武汉大学学报(医学版),2025,46(07):911-915. DOI: 10.14188/j.1671-8852.2024.0822.
WANG Fangling,LIU Sui,SHEN Yan,et al.Clinical therapeutic effect of medical ozonated water on stasis dermatitis[J].Medical Journal of Wuhan University,2025,46(07):911-915. DOI: 10.14188/j.1671-8852.2024.0822.
目的
2
观察分析医用臭氧水治疗淤积性皮炎的临床疗效。
方法
2
选择淤积性皮炎患者70例,随机分为治疗组(35例)和对照组(35例),治疗组在对照组外用药治疗基础上使用臭氧水局部泡浴或外敷,每日2次。观察并记录两组治疗2周前后改良版皮损面积严重程度评分(EASI)、瘙痒视觉模拟评分(VAS)、皮肤病生活质量评分(DLQI)的变化。
结果
2
与治疗前相比,两组患者治疗2周后EASI、VAS、DLQI均显著降低(均
P
<
0.05),且治疗组较对照组三项指标下降更显著(均
P
<
0.05)。治疗组35例患者皮损总有效率为97.14%,对照组35例中皮损总有效率为85.71%,总有效率治疗组优于对照组(
P
<
0.05)。
结论
2
在淤积性皮炎的治疗中,医用臭氧水有效、安全,可作为一种值得推广的临床治疗手段。
Objective
2
To observe the clinical therapeutic effect of medical ozonated water on stasis dermatitis.
Methods
2
Seventy patients with stasis dermatitis were enrolled and randomly divided into an experimental group (
n
=35) and a control group (
n
=35). The experimental group received topical medical ozonated water treatment twice daily in addition to the control group's topical medication. Modified eczema area and severity index (EASI)
visual analogue scale (VAS)
and dermatology life quality index (DLQI) scores were recorded in both groups after 2 weeks of treatment.
Results
2
Compared with baseline values
EASI
VAS
and DLQI scores in both groups showed significant reductions after 2 weeks (all
P
<
0.05)
with greater improvement observed in the experimental group (all
P
<
0.05). The total effective rate of skin lesions was 97.14% in the experimental group versus 85.71% in the control group. The total effective rate of skin lesions in the treatment group was better than that in the control group(
P
<
0.05).
Conclusion
2
Medical ozonated water is an effective and safe therapeutic option for stasis dermatitis
demonstrating clinical value worthy of broader application.
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