武汉大学中南医院眼科 湖北 武汉 430071
蒲黔梅,女,1997—,医学硕士生,主要从事眼肿瘤疾病相关研究,E‑mail:571720274@qq.com
严明,男,1972—,医学博士,副教授,博士研究生导师,主要从事眼表及遗传性眼病的基因诊断和机制相关研究,E‑mail:yanming72@whu.edu.cn
收稿:2024-02-02,
纸质出版:2025-03-25
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蒲黔梅,严明.677例眼科住院眼肿瘤病人的年龄分布特征[J].武汉大学学报(医学版),2025,46(03):327-334.
PU Qianmei,YAN Ming.The age characteristics distribution of hospitalized patients with ocular tumors in department of ophthalmology[J].Medical Journal of Wuhan University,2025,46(03):327-334.
蒲黔梅,严明.677例眼科住院眼肿瘤病人的年龄分布特征[J].武汉大学学报(医学版),2025,46(03):327-334. DOI: 10.14188/j.1671-8852.2024.0094.
PU Qianmei,YAN Ming.The age characteristics distribution of hospitalized patients with ocular tumors in department of ophthalmology[J].Medical Journal of Wuhan University,2025,46(03):327-334. DOI: 10.14188/j.1671-8852.2024.0094.
目的
2
分析眼肿瘤的组织病理学类型和年龄分布。
方法
2
回顾性分析2012年1月—2021年12月在眼科住院治疗的677例眼肿瘤患者的临床资料,以10岁为界限分析眼肿瘤不同解剖学部位、组织病理学类型和年龄的构成比。
结果
2
眼肿瘤在眼科住院病人中的占比呈三峰分布,三个高峰分别为0~9岁,20~29岁,60~69岁。眼部恶性肿瘤,以20~29岁为参照
0~9岁患病比例为参照组的0.966倍,10~19岁患病比例为参照组的0.95倍,20岁后患病的概率随着年龄的增长而增加,60岁开始到达稳定的最大概率(占21.63%)。年龄相关的变化显示前10类分布的眼部良性肿瘤类型有显著差异(
P
<
0.05)。
结论
2
不同眼肿瘤的发生类型、恶性程度和位置有显著差异,年龄是恶性眼部肿瘤的危险因素。
Objective
2
To analyze the histopathological types and age distribution of ocular tumors.
Methods
2
The clinical data of 677 patients with ocular tumors who were hospitalized in ophthalmology from January 2012 to December 2021 were retrospectively analyzed. The anatomical parts
histopathological types
and age distribution of ocular tumors were analyzed with a limit of 10 years old.
Results
2
The proportion of ocular tumors in ophthalmic hospitalized patients showed a three‑peak distribution
with the highest incidences occurring at ages 0⁃9
20⁃29
and 60⁃69. For ocular malignancies
compared to the reference group of 20⁃29 years old
the incidence ratio was 0.966 times in the 0⁃9 age group
0.95 times in the 10⁃19 age group
and the probability of diagnosis increased with age after 20 years
reaching a stable maximum probability at 60 years (21.63%). Age‑related changes showed significant differences among the top 10 distributions of ocular benign tumor types (
P
<
0.05).
Conclusion
2
There are significant differences in the occurrence type
malignant degree
and location of different ocular tumors. Age is the main risk factor for malignant ocular tumors.
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