性行为对10 mm以内输尿管结石排出效果的Meta分析

朱雅冰; 禹刚; 吴天鹏

doi:10.14188/j.1671-8852.2023.0348

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性行为对10 mm以内输尿管结石排出效果的Meta分析

综述与Meta分析 | 更新时间：2026-11-05

- 性行为对10 mm以内输尿管结石排出效果的Meta分析
- Meta‑analysis of the effect of sexual intercourse on promoting the discharge of ureteral stone less than 10 mm
- 武汉大学学报（医学版） 2025年46卷第3期页码：413-418
- 作者机构：
  
  1.武汉大学人民医院，重症医学科，湖北武汉 430060
  2.武汉大学人民医院，泌尿外科，湖北武汉 430060
- 作者简介：
  
  朱雅冰，女，1989—,主管护师，主要从事泌尿系重症疾病研究，E‑mail: 516748009@qq.com
  吴天鹏，男，1966—,医学博士，主任医师，教授，硕士生导师，主要从事泌尿外科疾病研究，E‑mail: drwutianpeng@aliyun.com
- 基金信息：
  
  中央高校基本科研业务费专项资金项目(2042022kf1090)
- DOI：10.14188/j.1671-8852.2023.0348
  中图分类号： R693⁺.4
- 收稿：2023-06-15，
  
  纸质出版：2025-03-25
- 稿件说明：
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朱雅冰,禹刚,吴天鹏.性行为对10 mm以内输尿管结石排出效果的Meta分析[J].武汉大学学报（医学版）,2025,46(03):413-418.

ZHU Yabing,YU Gang,WU Tianpeng.Meta‑analysis of the effect of sexual intercourse on promoting the discharge of ureteral stone less than 10 mm[J].Medical Journal of Wuhan University,2025,46(03):413-418.
朱雅冰,禹刚,吴天鹏.性行为对10 mm以内输尿管结石排出效果的Meta分析[J].武汉大学学报（医学版）,2025,46(03):413-418. DOI： 10.14188/j.1671-8852.2023.0348.

ZHU Yabing,YU Gang,WU Tianpeng.Meta‑analysis of the effect of sexual intercourse on promoting the discharge of ureteral stone less than 10 mm[J].Medical Journal of Wuhan University,2025,46(03):413-418. DOI： 10.14188/j.1671-8852.2023.0348.

摘要

目的

系统评价性行为促进10 mm以内输尿管结石排出的临床效果，为此提供相应循证医学证据。

方法

本研究检索并纳入了知网、万方、PubMed、Embase、Web of Science （WOS）及Cochrane Central Register of Controlled Trials (CENTRAL)中2023年5月31日前有关性行为促进输尿管结石排出的文献，提取排石率、排石时间及日需止疼药物剂次等数据，应用ADDIS 1.16.8进行贝叶斯网状Meta分析，应用STATA 16.0进行敏感性分析。

结果

纳入4篇随机对照试验（RCT）研究，共416名患者。患者结石直径均在10 mm以下，其被分为常规治疗组、性行为组（3~4次/周性行为）及坦索罗辛组。两两对比结果表明，性行为组排石率、排石时间及日需止疼剂次优于常规治疗组；性行为组排石率高于坦索罗辛组，但其排石时间及日需止疼剂次与坦索罗辛组无明显差异。敏感性分析提示，排石时间及日需止疼剂次（性行为组

常规治疗组）分析结果稳健。贝叶斯网状Meta分析结果表明，研究模型一致性及收敛性良好，常规治疗组排石率明显低于性行为组及坦索罗辛组，性行为组排石率明显高于坦索罗辛组；常规治疗组日需止疼药物剂次明显高于性行为组。排石率、排石时间及日需止疼药物剂次等级排序结果皆提示：性行为组

坦索罗辛组

常规治疗组。

结论

对于输尿管下段10 mm以内结石而言，3~4次/周性行为可促进其排出，可能是一种有效的非手术治疗手段。

Abstract

Objective

To systematically evaluate the clinical effect of sexual intercourse on ureteral stones less than 10 mm and to provide evidence‑based medical evidence.

Methods

We searched and included studies about the effect of sexual intercourse on the lower ureteral stone before May 31

2023

in CNKI

WanFang

PubMed

Embase

Web of Science （WOS）

and Cochrane Central Register of Controlled Trials (CENTRAL)

and extracted some data (the stone‑removal rate

stone‑removal time

daily analgesic doses and so on) for further analysis using ADDIS 1.16.8 and STATA 16.0.

Results

A total of four randomized controlled trial (RCT) studies were finally included

with a total of 416 patients. Their stones were less than 10 mm in diameter and were divided into the conventional treatment group

sexual intercourse group (3‑4 times/week)

and tamsulosin group. The results of pairwise comparison showed that the stone‑free rate

stone‑free time

and daily analgesic dose in the coitus group were better than those in the conventional treatment group. The stone‑free rate in the coitus group was higher than that in the tamsulosin group

but the stone‑free time and daily analgesic dose were both higher in the coitus group than in the tamsulosin group. Sensitivity analysis showed that the results of stone‑free time and daily analgesic dose (the coitus group

the conventional treatment group) were robust. Bayesian network meta‑analysis results showed that the model consistency and convergence were good. The stone‑free rate of the conventional treatment group was significantly lower than that of the coitus group and tamsulosin group. The stone‑free rate of the coitus group was significantly higher than that of the tamsulosin group. The daily analgesic dose in the conventional treatment group was significantly higher than that in the coitus group. The ranking results of stone‑free rate

stone‑free time

and daily analgesic dose showed that the coitus group

the tamsulosin group

the conventional treatment group.

Conclusion

For stones under 10 mm in the lower ureter

sexual intercourse 3‑4 times/week can promote their discharge

which may be an effective non‑surgical treatment.

关键词

Keywords

references

HEALY K A , SHAH O . MET for distal ureteral calculi: not all stones are created equal [J ] . Nat Rev Urol , 2018 , 15 : 210 ‑ 211 .

DE CONINCK V , ANTONELLI J , CHEW B , et al . Medical expulsive therapy for urinary stones: Future trends and knowledge gaps [J ] . Eur Urol , 2019 , 76 ( 5 ): 658 ‑ 666 .

DOLUOGLU O G , DEMIRBAS A , KILINC M F , et al . Can sexual intercourse be an alternative therapy for distal ureteral stones? A prospective, randomized, controlled study [J ] . Urology , 2015 , 86 ( 1 ): 19 ‑ 24 .

ABDEL‑KADER M S . Evaluation of the efficacy of sexual intercourse in expulsion of distal ureteric stones [J ] . Int Urol Nephrol , 2017 , 49 ( 1 ): 27 ‑ 30 .

BAYRAKTAR Z , ALBAYRAK S . Sexual intercourse as a new option in the medical expulsive therapy of distal ureteral stones in males: A prospective, randomized, controlled study [J ] . Int Urol Nephrol , 2017 , 49 ( 11 ): 1941 ‑ 1946 .

TURGUT H . Evaluation of the efficacy of sexual intercourse on distal ureteral stones in women: A prospective, randomized, controlled study [J ] . Int Urol Nephrol , 2021 , 53 ( 3 ): 409 ‑ 413 .

石天昊 , 冯燕飞 , 王坚 , 等 . 药物治疗输尿管结石研究进展 [J ] . 浙江中西医结合杂志 , 2021 , 31 ( 7 ): 681 ‑ 684 .

SHI T H , FENG Y F , WANG J , et al . Research progress in drug treatment of ureteral calculi [J ] . Zhejiang J Integr Tradit Chin West Med , 2021 , 31 ( 7 ): 681 ‑ 684 .

ISELIN C E , NY L , LARSSON B , et al . The nitric oxide synthase/nitric oxide and heme oxygenase/carbon monoxide pathways in the human ureter [J ] . Eur Urol , 1998 , 33 ( 2 ): 214 ‑ 221 .

杨春 , 辛钟成 , 付杰 , 等 . 淫羊藿苷对兔阴蒂海绵体平滑肌细胞NO及NOS活性的影响 [J ] . 中国男科学杂志 , 2005 , 19 ( 1 ): 6 ‑ 10 .

YANG C , XIN Z C , FU J , et al . Effects of Icariin on NO production and NOS activity of rabbit clitoral corporal smooth muscle cells [J ] . Chin J Androl , 2005 , 19 ( 1 ): 6 ‑ 10 .

BULBUL E , SENER E F , GUNAY N E , et al . A role of the endothelial nitric oxide system in acute renal colic caused by ureteral stone [J ] . Am J Emerg Med , 2018 , 36 ( 2 ): 266 ‑ 270 .

李广宇 . 中西医结合配合运动治疗肾及输尿管结石69例疗效分析 [J ] . 实用中医药杂志 , 2005 , 21 ( 12 ): 738 ‑ 739 .

LI G Y . Clinical analysis of 69 cases of renal and ureteral calculi treated by combination of traditional Chinese and western medicine and exercise [J ] . J Pract Tradit Chin Med , 2005 , 21 ( 12 ): 738 ‑ 739 .

LI W F , MAO Y , LU C , et al . Role of sexual intercourse after shockwave lithotripsy for distal ureteral stones: A randomized controlled trial [J ] . Urol J , 2020 , 17 ( 2 ): 134 ‑ 138 .

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