1. 河南省人民医院内分泌代谢病科,郑州
2. 河南省人民医院康复科,郑州
纸质出版:2024
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杨慧慧, 杨阳, 李亚昆, 等. 骶神经根功能性磁刺激治疗糖尿病神经源性膀胱的疗效观察[J]. 中华物理医学与康复杂志, 2024,46(9):817-821.
杨慧慧, 杨阳, 李亚昆, et al. 骶神经根功能性磁刺激治疗糖尿病神经源性膀胱的疗效观察[J]. 2024, 46(9): 817-821.
目的探讨骶神经根功能性磁刺激(FMS)治疗糖尿病神经源性膀胱(DNB)的临床疗效。方法采用随机数字表法将134例DNB患者分为观察组及对照组
每组67例。2组患者均给予常规药物治疗及膀胱功能训练
观察组患者在此基础上辅以骶神经根FMS干预。于治疗前、治疗4周后对2组患者排尿相关指标及尿流动力学参数进行检测
并对2组患者临床疗效进行评定。结果治疗4周后2组患者日均单次排尿量均较治疗前显著增加(P<0.05)
日均排尿次数、日均尿失禁次数均较治疗前显著减少(P<0.05)
并且观察组治疗后日均单次排尿量[(196.9±31.7)ml]较对照组显著增加(P<0.05)
日均排尿次数[(8.87±1.42)次/天]及日均尿失禁次数[(3.04±1.93)次/天]均显著少于对照组(P<0.05)。治疗后2组患者最大尿流率时逼尿肌压力(Pdet-Qmax)、膀胱初始尿意容量(BS)、膀胱残余尿量(RUV)均较治疗前显著降低(P<0.05)
而最大尿流率(MFR)则显著升高(P<0.05)
并且治疗后观察组Pdet-Qmax[(26.49±2.47)cmH2O]、BS[(288.11±26.04)ml]及RUV[(70.36±23.77)ml]均显著低于对照组水平
MFR[(18.94±3.18)ml/s]则显著高于对照组水平(P<0.05)。治疗后观察组总有效率(88.06%)较对照组总有效率(71.64%)显著增高(P<0.05)。结论在常规膀胱功能训练基础上辅以骶神经根FMS干预
能进一步促进DNB患者膀胱功能重建
改善尿流动力学参数
提高患者生活质量
该联合疗法值得临床推广、应用。
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