Characteristics of clinical and CT imaging and their relationship to the postoperative pathology in lung cancer with cystic airspaces

DONG Xinyang; LI Ting; ZHANG Kemeng; GUO Yang; LIAO Meiyan

doi:10.14188/j.1671-8852.2025.0155

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Characteristics of clinical and CT imaging and their relationship to the postoperative pathology in lung cancer with cystic airspaces

更新时间：2026-11-05

- Characteristics of clinical and CT imaging and their relationship to the postoperative pathology in lung cancer with cystic airspaces
- Medical Journal of Wuhan University Vol. 46, Issue 7, Pages: 895-899(2025)
- 作者机构：
  
  武汉大学中南医院医学影像科湖北武汉 430071
- 作者简介：
- 基金信息：
- DOI：10.14188/j.1671-8852.2025.0155
  CLC： R816.4
- Received：24 February 2025，
  
  Published：25 July 2025
- 稿件说明：
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董鑫扬,李婷,张可萌等.伴囊腔的肺癌临床、CT影像特征与术后病理相关性[J].武汉大学学报（医学版）,2025,46(07):895-899.

DONG Xinyang,LI Ting,ZHANG Kemeng,et al.Characteristics of clinical and CT imaging and their relationship to the postoperative pathology in lung cancer with cystic airspaces[J].Medical Journal of Wuhan University,2025,46(07):895-899.
董鑫扬,李婷,张可萌等.伴囊腔的肺癌临床、CT影像特征与术后病理相关性[J].武汉大学学报（医学版）,2025,46(07):895-899. DOI： 10.14188/j.1671-8852.2025.0155.

DONG Xinyang,LI Ting,ZHANG Kemeng,et al.Characteristics of clinical and CT imaging and their relationship to the postoperative pathology in lung cancer with cystic airspaces[J].Medical Journal of Wuhan University,2025,46(07):895-899. DOI： 10.14188/j.1671-8852.2025.0155.

摘要

目的

分析伴囊腔的肺癌临床、CT影像特征与术后病理的相关性。

方法

回顾性分析2017年7月至2023年10月武汉大学中南医院手术伴囊腔的肺癌的临床、CT影像及病理资料，将其中最常见的肺腺癌病例按病理亚型分为低危组和高危组，采用单因素及多因素Logistic回归分析筛选伴囊腔的肺腺癌高危组的相关危险因素。

结果

伴囊腔的肺癌107例，男性75例（70.1%），65例（60.7%）患者有吸烟史，64例（59.8%）无明显临床症状。CT图像形态多呈现薄壁、单囊、囊腔内支气管血管束穿行，53例（49.5%）可见胸膜凹陷征。病灶形态学分为Ⅰ型23例（21.5%），Ⅱ型15例（14.0%），Ⅲ型41例（38.3%），Ⅳ型28例（26.2%）。病灶最长径7~83 mm，囊腔最长径2~80 mm，囊壁厚度0.4~21 mm；58个囊壁结节厚度4~30 mm。93例腺癌（87.0%），其中低危组38例，高危组55例，多因素Logistic回归结果显示囊腔厚壁是高危组伴囊腔的肺腺癌的独立危险因素。

结论

伴囊腔的肺癌以腺癌为主，囊壁厚度是高危组伴囊腔的肺腺癌的独立危险因素。

Abstract

Objective

To report the clinical

CT imaging

and pathological characteristics of lung cancer with cystic airspaces and analyze the correlation between these features and postoperative pathology.

Methods

A retrospective analysis of clinical

CT imaging

and pathological data for lung cancer with cystic airspaces was conducted from July 2017 to October 2023. Lung adenocarcinoma was categorized into low⁃risk and high⁃risk groups based on pathological subtypes. Univariate and multivariate logistic regression analyses were performed to identify risk factors related to the high⁃risk group of lung cancer with cystic airspaces.

Results

A total of 107 cases of cystic lung cancer with cystic airspaces were included in the study. Among them

75 were males (70.1%). Among the patients

65 (60.7%) had a history of smoking

and 64 (59.8%) exhibited no obvious clinical symptoms. The CT imaging typically presents as thin‑walled

single cysts with bronchovascular bundles traversing the cystic cavity. Pleuritic retraction was observed in 53 cases (49.5%). The lesion morphology was classified as follows: Type Ⅰ in 23 cases (21.5%)

Type Ⅱ in 15 cases (14.0%)

Type Ⅲ in 41 cases (38.3%)

and Type Ⅳ in 28 cases (26.2%). The maximum diameter of the lesions ranged from 7 to 83 mm

while the cystic components measured 2–80 mm

with cyst wall thickness varying between 0.4 and 21 mm. Additionally

58 cyst wall nodules exhibited a thickness of 4–30 mm. Adenocarcinoma was diagnosed in 93 cases (87.0%)

with 38 in the low‑risk group and 55 in the high‑risk group. The multivariate logistic regression analysis result indicated that thick‑walled cysts are an independent risk factor for the high‑risk group of cystic lung adenocarcinoma.

Conclusion

Adenocarcinoma is the most common histological type among lung cancers with cystic features

and increased cyst wall thickness independently identifies high⁃risk subgroups.

关键词

Keywords

references

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