Efficacy analysis of tubeless percutaneous nephrolithotomy in the treatment of HIV positive patients with kidney calculi

CAO Chuxiao; WANG Yongzhi; LIU Tongzu; ZHANG Lin

doi:10.14188/j.1671-8852.2024.0794

您当前的位置：

首页 >

文章列表页 >

Efficacy analysis of tubeless percutaneous nephrolithotomy in the treatment of HIV positive patients with kidney calculi

更新时间：2026-11-05

- Efficacy analysis of tubeless percutaneous nephrolithotomy in the treatment of HIV positive patients with kidney calculi
- Medical Journal of Wuhan University Vol. 46, Issue 5, Pages: 666-669(2025)
- 作者机构：
  
  1.荆门市中医医院泌尿外科湖北荆门 448000
  2.武汉大学中南医院泌尿外科湖北武汉 430071
- 作者简介：
- 基金信息：
- DOI：10.14188/j.1671-8852.2024.0794
  CLC： R692.4
- Received：21 October 2024，
  
  Published：25 May 2025
- 稿件说明：
移动端阅览
曹楚潇,王永志,刘同族等.HIV阳性肾结石患者行无管化经皮肾镜碎石取石术的疗效分析[J].武汉大学学报（医学版）,2025,46(05):666-669.

CAO Chuxiao,WANG Yongzhi,LIU Tongzu,et al.Efficacy analysis of tubeless percutaneous nephrolithotomy in the treatment of HIV positive patients with kidney calculi[J].Medical Journal of Wuhan University,2025,46(05):666-669.
曹楚潇,王永志,刘同族等.HIV阳性肾结石患者行无管化经皮肾镜碎石取石术的疗效分析[J].武汉大学学报（医学版）,2025,46(05):666-669. DOI： 10.14188/j.1671-8852.2024.0794.

CAO Chuxiao,WANG Yongzhi,LIU Tongzu,et al.Efficacy analysis of tubeless percutaneous nephrolithotomy in the treatment of HIV positive patients with kidney calculi[J].Medical Journal of Wuhan University,2025,46(05):666-669. DOI： 10.14188/j.1671-8852.2024.0794.

摘要

目的

探讨无管化经皮肾镜碎石取石术治疗HIV阳性肾结石患者的有效性和安全性。

方法

回顾性分析武汉大学中南医院2015年6月至2019年6月肾结石患者，STONE评分均为6分，由同一术者主刀，行无管化经皮肾镜碎石取石术，术后不留置肾造瘘管，留置输尿管支架管和导尿管。HIV阳性组患者11例，HIV阴性组患者26例。比较两组的结石清除率、术后并发症、手术时间、术后住院天数。

结果

所有患者均无脓毒血症、肾功能不全、大出血等重大并发症，HIV阳性组和HIV阴性组的结石清除率及术后住院天数，差异均无统计学意义；HIV阳性组的手术时间明显高于HIV阴性组，分别为（93.73±3.45） min和（83.42±2.59） min。

结论

无管化经皮肾镜碎石取石术治疗HIV阳性肾结石(STONE评分为6分)安全，效果满意，对HIV阳性肾结石患者有肯定的临床价值。

Abstract

Objective

To evaluate the efficacy and safety of tubeless percutaneous nephrolithotomy (PCNL) in the treatment of HIV positive patients with kidney calculi.

Methods

A retrospective analysis was performed on the patients with kidney calculi in Zhongnan Hospital of Wuhan University from June 2015 to June 2019. All patients had an S.T.O.N.E score of 6 and underwent tubeless PCNL performed by the same surgeon. Postoperatively

no nephrostomy tube was placed

but a ureteral stent and urinary catheter were retained. There were 11 patients in the HIV positive group and 26 patients in the HIV negative group

and the stone clearance rate

postoperative complications

operation time

and postoperative hospital stay were compared between the two groups.

Results

No patient experienced major complications such as sepsis

renal insufficiency

or significant bleeding. There was no significant difference in postoperative hospital stay and the stone clearance rates between the HIV positive and HIV negative groups. The operation time in the HIV positive group was significantly longer than that in the HIV negative group

as (93.73±3.45) min versus (83.42±2.59) min

respectively.

Conclusion

Tubeless PCNL is a safe and effective treatment for HIV⁃positive patients with renal calculi (S.T.O.N.E score of 6)

demonstrating satisfactory outcomes and significant clinical value for this patient population.

关键词

Keywords

references

HE N . Research progress in the epidemiology of HIV/AIDS in China [J ] . China CDC Wkly , 2021 , 3 ( 48 ): 1022 ‑ 1030 .

ROOMANEY R A , VAN WYK B , PILLAY‑VAN WYK V . Aging with HIV: Increased risk of HIV comorbidities in older adults [J ] . Int J Environ Res Public Health , 2022 , 19 ( 4 ): 2359 .

SKOLARIKOS A , JUNG H , NEISIUS A , et al . EAU Guidelines on urolithiasis [R/OL ] . Guidelines OfficeEAU, Arnhem, Netherlands, 2024 . http://uroweb.org/guidelines/compilations-of-all-guidelines/ http://uroweb.org/guidelines/compilations-of-all-guidelines/ .

吴梦华 , 张愚 , 郑鑫 . HIV阳性患者合并上尿路结石的单中心诊疗经验并结石成分分析 [J ] . 北京医学 , 2022 , 44 ( 3 ): 227 ‑ 231 .

WU M H , ZHANG Y , ZHENG X . Single center diagnosis and treatment experience of HIV positive patients with upper urinary tract stones and analysis of stone components [J ] . Beijing Med J , 2022 , 44 ( 3 ): 227 ‑ 231 .

OKHUNOV Z , FRIEDLANDER J I , GEORGE A K , et al . STONE nephrolithometry: Novel surgical classification system for kidney calculi [J ] . Urology , 2013 , 81 ( 6 ): 1154 ‑ 1159 .

杨文斌 , 张茨 . 无管化经皮肾镜碎石取石术的研究进展 [J ] . 中国综合临床 , 2016 , 32 ( 1 ): 93 ‑ 96 .

YANG W B , ZHANG C . Advances in tubeless percutaneous neprolithotomy [J ] . Clin Med China , 2016 , 32 ( 1 ): 93 ‑ 96 .

张林 , 刘同族 , 王行环 , 等 . 输尿管软镜碎石取石术治疗2 cm以上肾结石的临床观察 [J ] . 武汉大学学报(医学版) , 2017 , 38 ( 5 ): 812 ‑ 814 .

ZHANG L , LIU T Z , WANG X H , et al . Flexible ureteroscope with holmium laser lithotripsy for renal stones of more than 2 cm in diameter [J ] . Med J Wuhan Univ , 2017 , 38 ( 5 ): 812 ‑ 814 .

程传宇 , 何恒 , 张二军 , 等 . 电子输尿管软镜钬激光碎石术在人免疫缺陷病毒感染肾结石患者治疗中的应用 [J ] . 中华泌尿外科杂志 , 2016 , 37 ( 12 ): 928 ‑ 931 .

CHENG C Y , HE H , ZHANG E J , et al . Application of flexible ureteroscopy combined with Holmium laser lithotripsy for kidney calculi patients with HIV positive [J ] . Chin J Urol , 2016 , 37 ( 12 ): 928 ‑ 931 .

赵洋乐 , 纪世琪 , 韩志兴 , 等 . 输尿管软镜碎石术治疗肾结石合并HIV感染的疗效分析 [J ] . 临床泌尿外科杂志 , 2022 , 37 ( 2 ): 95 ‑ 99 .

ZHAO Y L , JI S Q , HAN Z X , et al . Analysis of flexible ureteroscopic lithotripsy on kidney stones combined with HIV infection [J ] . J Clin Urol , 2022 , 37 ( 2 ): 95 ‑ 99 .

叶章群 . 泌尿系结石诊断治疗指南 [M ] . 北京 : 科学出版社 , 2022 : 398 ⁃ 402 .

YE Z Q . Guidelines on urolithiasis [M ] . Beijing : China Science Publishing & Media Ltd. , 2022 : 398 ⁃ 402 .

李南南 , 唐智旺 , 汪志民 , 等 . 经皮肾镜碎石术治疗复杂性肾结石合并艾滋病病毒感染患者68例 [J ] . 实用医学杂志 , 2021 , 37 ( 4 ): 463 ‑ 467 .

LI N N , TANG Z W , WANG Z M , et al . Percutaneous nephrolithotomy for complex renal calculi complicated with HIV infection in 68 patients [J ] . J Pract Med , 2021 , 37 ( 4 ): 463 ‑ 467 .

TORRICELLI F C M , MONGA M , DALL'AQUA V , et al . Percutaneous nephrolithotomy in immunocompromised patients: Outcomes from a matched case‑control study [J ] . J Endourol , 2016 , 30 ( 12 ): 1326 ‑ 1331 .

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Analysis of sleep disorders status and influencing factors in people living with HIV/AIDS in Wuhan: A mixed‐methods study

Effect of ART therapy on the predictors of atherosclerosis TyG index and MHR in HIV⁃infected patients

HIV-Related Non-Hodgkin Lymphoma with Multiple Organ Damage: Report of One Case and Review of Literature

Changes of sIgA in Saliva of HIV Infected Patients with Oral Candidiasis

The mechanism and preventive therapeutic value of nuclear factor erythroid 2⁃related factor 2 in ischemic stroke

Related Author

ZHANG Lin

CAO Chuxiao

WU Mengyuan

LIU Dan

CHEN Xiaoting

HUANG Xiaodong

XI Maomao

SHI Lei

Related Institution

School of Public Health, Tongji Medical College, Huazhong University of Science and Technology

Wuhan Hongshan Center for Disease Control and Prevention

Department of Infectious Diseases, Wuhan Third Hospital

Institute of Burn Research, Wuhan Third Hospital

Office of the Hospital Party Committee, Wuhan Third Hospital

AI问答

⁰