Application effect of kinesitherapy combined with brain reflex therapy in patients with chronic schizophrenia

LIU Jianbing; JIA Qian; ZOU Yao; CHEN Nian; YANG Ping

doi:10.14188/j.1671-8852.2024.0677

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Application effect of kinesitherapy combined with brain reflex therapy in patients with chronic schizophrenia

更新时间：2026-11-05

- Application effect of kinesitherapy combined with brain reflex therapy in patients with chronic schizophrenia
- Medical Journal of Wuhan University Vol. 46, Issue 10, Pages: 1343-1347(2025)
- 作者机构：
  
  1.苏州市广济医院，精神康复科，江苏苏州 215000
  2.苏州市广济医院，精神二科，江苏苏州 215000
- 作者简介：
- 基金信息：
- DOI：10.14188/j.1671-8852.2024.0677
  CLC： R749.3
- Received：05 September 2024，
  
  Published：25 October 2025
- 稿件说明：
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刘建兵,贾倩,邹瑶等.运动疗法联合脑反射治疗在慢性精神分裂症患者中的应用效果[J].武汉大学学报（医学版）,2025,46(10):1343-1347.

LIU Jianbing,JIA Qian,ZOU Yao,et al.Application effect of kinesitherapy combined with brain reflex therapy in patients with chronic schizophrenia[J].Medical Journal of Wuhan University,2025,46(10):1343-1347.
刘建兵,贾倩,邹瑶等.运动疗法联合脑反射治疗在慢性精神分裂症患者中的应用效果[J].武汉大学学报（医学版）,2025,46(10):1343-1347. DOI： 10.14188/j.1671-8852.2024.0677.

LIU Jianbing,JIA Qian,ZOU Yao,et al.Application effect of kinesitherapy combined with brain reflex therapy in patients with chronic schizophrenia[J].Medical Journal of Wuhan University,2025,46(10):1343-1347. DOI： 10.14188/j.1671-8852.2024.0677.

摘要

目的

探讨运动疗法联合脑反射治疗在慢性精神分裂症患者中的应用效果。

方法

选取苏州市广济医院2023年1月—2024年5月期间收治的慢性精神分裂症患者106例，随机分成对照组和研究组（各53例）。对照组在常规抗精神病药物治疗的同时实施脑反射治疗，研究组在对照组基础上给予运动疗法。比较两组阴性症状[阴性症状评定量表（SANS）]、康复效果[morning side康复状态量表（MRSS）]、心理韧性[心理韧性量表（CD⁃RISC）]、认知功能[蒙特利尔认知评估量表（MoCA）]及生活质量[精神分裂症患者生活质量量表（SQLS）]。

结果

干预后，两组SANS、MRSS和SQLS的各维度评分及总分均降低，且研究组均低于对照组（

0.05）；两组CD⁃RISC和MoCA各维度评分及总分均升高，且研究组均高于对照组（

0.05）。

结论

针对慢性精神分裂症患者，运动疗法联合脑反射治疗具有确切康复效果，可改善其阴性症状，提高心理韧性水平和生活质量，促进认知功能恢复。

Abstract

Objective

To explore the application effect of kinesitherapy combined with brain reflex therapy in patients with chronic schizophrenia.

Methods

A total of 106 patients with chronic schizophrenia admitted to Suzhou Guangji Hospital from January 2023 to May 2024 were randomly divided into control group and study group (53 cases each). The control group was treated with conventional antipsychotic drugs and brain reflex therapy

while the study group was given kinesitherapy based on the control group. The negative symptoms (scale for assessment of negative symptoms (SANS))

rehabilitation effect (morning side rehabilitation status scale (MRSS))

psychological resilience (Connor⁃Davidson resilience scale (CD⁃RISC))

cognitive function (Montreal cognitive assessment scale (MoCA)) and quality of life (schizophrenia quality of life scale (SQLS)) were compared between the two groups.

Results

After the intervention

scores across all dimensions and total scores of SANS

MRSS

and SQLS decreased in both groups

with the study group showing significantly lower scores than the control group (

0.05). Conversely

scores for all dimensions and total scores of CD⁃RISC and MoCA increased in both groups

with the study group demonstrating significantly higher scores than the control group (

0.05).

Conclusion

For patients with chronic schizophrenia

kinesitherapy combined with brain reflex therapy demonstrates definite rehabilitation efficacy

improving negative symptoms

enhancing psychological resilience and quality of life

and promoting the recovery of cognitive function.

关键词

Keywords

references

PRIOL A C , DENIS L , BOULANGER G , et al . Detection of morphological abnormalities in schizophrenia: An important step to identify associated genetic disorders or etiologic subtypes [J ] . Int J Mol Sci , 2021 , 22 ( 17 ): 9464 .

李丽 , 陈学全 , 费龙才 . TBS模式下高频重复经颅磁刺激辅助治疗慢性精神分裂症的效果观察 [J ] . 临床和实验医学杂志 , 2023 , 22 ( 9 ): 938 ‑ 941 .

LI L , CHEN X Q , FEI L C . Effect of high‑frequency rTMS under TBS mode in treating chronic schizophrenia [J ] . J Clin Exp Med , 2023 , 22 ( 9 ): 938 ‑ 941 .

张维珍 , 刘梅 , 张兰 , 等 . 深层肌肉刺激联合脑反射治疗仪对帕金森病患者平衡功能吞咽功能的影响 [J ] . 中国实用神经疾病杂志 , 2023 , 26 ( 2 ): 175 ‑ 179 .

ZHANG W Z , LIU M , ZHANG L , et al . Effects of deep muscle stimulation combined with brain reflex therapeutic instrument on balance function and swallowing function in patients with Parkinson's disease [J ] . Chin J Pract Nerv Dis , 2023 , 26 ( 2 ): 175 ‑ 179 .

武丹娜 , 沈瑞红 , 赵伟鹏 , 等 . 经颅磁脑反射电疗仪与针刺治疗卒中后肩手综合征对比研究 [J ] . 河北中医 , 2023 , 45 ( 7 ): 1128 ‑ 1131 .

WU D N , SHEN R H , ZHAO W P , et al . Comparative study of transcranial magnetic stimulation therapy and acupuncture on post‑stroke shoulder‑hand syndrome [J ] . Hebei J Tradit Chin Med , 2023 , 45 ( 7 ): 1128 ‑ 1131 .

REN F F , HILLMAN C H , WANG W G , et al . Effects of aerobic exercise on cognitive function in adults with major depressive disorder: A systematic review and meta‑analysis [J ] . Int J Clin Health Psychol , 2024 , 24 ( 2 ): 100447 .

International Advisory Group for the Revision of ICD⁃ 10 Mental and Behavioural Disorders. A conceptual framework for the revision of the ICD‑10 classification of mental and behavioural disorders [J ] . World Psychiatry , 2011, 10 ( 2 ): 86 ‑ 92 .

SINGH S , KUMAR N , VERMA R , et al . The safety and efficacy of adjunctive 20‑Hz repetitive transcranial magnetic stimulation for treatment of negative symptoms in patients with schizophrenia: A double‑blinded, randomized, sham‑controlled study [J ] . Indian J Psychiatry , 2020 , 62 ( 1 ): 21 ‑ 29 .

冯辉 , 姜益明 , 陈玉明 , 等 . 行为技能训练对社区与住院精神分裂症患者康复效果的对照研究 [J ] . 中国康复医学杂志 , 2011 , 26 ( 6 ): 561 ‑ 565 .

FENG H , JIANG Y M , CHEN Y M , et al . Control study about behavioral skills training on the rehabilitation of schizophrenic patients from communities and hospital [J ] . Chin J Rehabil Med , 2011 , 26 ( 6 ): 561 ‑ 565 .

FARIA ANJOS J , HEITOR DOS SANTOS M J , RIBEIRO M T , et al . Connor‑Davidson resilience scale: Validation study in a Portuguese sample [J ] . BMJ Open , 2019 , 9 ( 6 ): e026836 .

张顺 , 李娜 , 张素娟 , 等 . 精神分裂症患者血清CRP、Hcy和SHBG水平变化及与临床症状和认知功能相关性研究 [J ] . 临床和实验医学杂志 , 2021 , 20 ( 21 ): 2338 ‑ 2341 .

ZHANG S , LI N , ZHANG S J , et al . Changes of serum CRP, Hcy and SHBG levels in patients with schizophrenia and their correlation with clinical symptoms and cognitive function [J ] . J Clin Exp Med , 2021 , 20 ( 21 ): 2338 ‑ 2341 .

骆宏 , 罗南 , 王义强 , 等 . 精神分裂症患者生活质量量表信效度检验与应用 [J ] . 中国心理卫生杂志 , 2003 , 17 ( 3 ): 172 ‑ 174 .

LUO H , LUO N , WANG Y Q , et al . Reliability and validity of the schizophrenia quality of life scale [J ] . Chin Ment Health J , 2003 , 17 ( 3 ): 172 ‑ 174 .

黄梅 , 朱明 , 吴尚辉 . 基于团体课形式的感觉统合训练对男性慢性精神分裂症患者的影响 [J ] . 中国医药导报 , 2023 , 20 ( 25 ): 111 ‑ 114 .

HUANG M , ZHU M , WU S H . Effect of group class‑based sensory integration training in male patients with chronic schizophrenia [J ] . China Med Her , 2023 , 20 ( 25 ): 111 ‑ 114 .

ANG M J , LEE S , KIM J C , et al . Behavioral tasks evaluating schizophrenia‑like symptoms in animal models: A recent update [J ] . Curr Neuropharmacol , 2021 , 19 ( 5 ): 641 ‑ 664 .

岳曼曼 , 马瑞 , 吴远雄 , 等 . 团体游戏治疗对改善住院女性精神分裂症患者认知功能和阴性症状的效果 [J ] . 四川精神卫生 , 2024 , 37 ( 3 ): 232 ⁃ 236 .

YUE M M , MA R , WU Y X , et al . Efficacy of group play therapy on cognitive function and negative symptoms in hospitalized female patients with schizophrenia [J ] . Sichuan Ment Health , 2024 , 37 ( 3 ): 232 ⁃ 236 .

毛静宇 , 易峰 , 梅佳 , 等 . θ短阵快速脉冲模式的重复经颅磁刺激对慢性精神分裂症阴性症状及社会功能的疗效研究 [J ] . 精神医学杂志 , 2019 , 32 ( 3 ): 183 ‑ 187 .

MAO J Y , YI F , MEI J , et al . Effects of repetitive transcranial magnetic stimulation with Theta burst stimulation paradigm on negative symptoms and social functions in patients with chronic schizophrenia [J ] . J Psychiatry , 2019 , 32 ( 3 ): 183 ‑ 187 .

顾静莲 , 闵海瑛 , 沈颖 , 等 . 低强度运动疗法对住院慢性精神分裂症患者的影响 [J ] . 中华现代护理杂志 , 2016 , 22 ( 19 ): 2700 ‑ 2703 .

GU J L , MIN H Y , SHEN Y , et al . Effect of low‑intensity exercise therapy on the hospitalized patients with chronic schizophrenia [J ] . Chin J Mod Nurs , 2016 , 22 ( 19 ): 2700 ‑ 2703 .

陈秋莹 , 张琪 , 周锦 , 等 . 有氧运动通过增加神经调节蛋白1水平对精神分裂症患者认知功能的影响 [J ] . 临床精神医学杂志 , 2023 , 33 ( 6 ): 435 ‑ 438 .

CHEN Q Y , ZHANG Q , ZHOU J , et al . Effects of aerobic exercise on cognitive function by upregulating neuregulin‑1 in patients with schizophrenia [J ] . J Clin Psychiatry , 2023 , 33 ( 6 ): 435 ‑ 438 .

MITSADALI I , GRAYSON B , IDRIS N F , et al . Aerobic exercise improves memory and prevents cognitive deficits of relevance to schizophrenia in an animal model [J ] . J Psychopharmacol , 2020 , 34 ( 7 ): 695 ‑ 708 .

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