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脊髓损伤是一种致残率较高的疾病
常导致感觉、运动和自主神经功能受损。磁刺激作为近年来兴起的一种无创性治疗方法
被广泛运用于脊髓等中枢神经系统疾病的治疗中。本文就磁刺激在脊髓损伤后运动功能障碍、痉挛、神经病理性疼痛、神经源性膀胱、呼吸功能障碍中的应用及其作用机制的研究进展作一综述
以期为磁刺激的临床应用提供理论参考。
罗丽华,吴东宇,王雨生,马二浩,董继革.重复经颅磁刺激联合发散式冲击波治疗创伤性脊髓损伤患者肌肉痉挛的疗效观察[J].中国康复医学杂志,2023(12).
陶媛媛,张大伟,冯晓燕,朱心玮,焦乐,蔡萍,陈庆梅,韩立影,朱红军.脊髓重复磁刺激对骶上脊髓损伤后神经源性膀胱的影响[J].中华物理医学与康复杂志,2023(10).
邹凡,管蔚畅,蔺俊斌.重复经颅磁刺激联合肌内效贴对不完全性脊髓损伤患者下肢痉挛状态的影响[J].神经损伤与功能重建,2023(01).
王宏宇,邹颖,元香南,周凤华,张立新.脊髓损伤患者肺康复治疗的研究进展[J].中国医科大学学报,2022(08).
陈铖,夏婷,张少武.骶神经根磁刺激联合行为治疗对脊髓损伤后膀胱过度活动症的临床疗效观察[J].神经损伤与功能重建,2022(06).
蒋金金,宋娜,胡文清,马琪.重复磁刺激治疗脊髓损伤后神经源性膀胱的研究进展[J].河北医科大学学报,2022(04).
Ting-Ting Sun,Guang-Yue Zhu,Ya Zheng,Ye-Ran Mao,Qi-Long Hu,Gong-Ming Song,Rong Xu,Qi Yang,Dan Zhao,Xu-Yun Hua,Dong-Sheng Xu.Effects of paired associative magnetic stimulation between nerve root and cortex on motor function of lower limbs after spinal cord injury:study protocol for a randomized controlled trial[J].Neural Regeneration Research,2022(11).
Ya Zheng,Dan Zhao,Dong-Dong Xue,Ye-Ran Mao,Ling-Yun Cao,Ye Zhang,Guang-Yue Zhu,Qi Yang,Dong-Sheng Xu.Nerve root magnetic stimulation improves locomotor function following spinal cord injury with electrophysiological improvements and cortical synaptic reconstruction[J].Neural Regeneration Research,2022(09).
陆飞,闫振壮,苏清伦,马金亚,苏敏.不同频率高频磁刺激对脊髓损伤后神经源性膀胱患者治疗效果的比较[J].中国康复医学杂志,2021(07).
张秀,华文洁,李素.脊髓损伤神经源性膀胱患者尿路感染相关危险因素的回顾性研究[J].中国康复,2021(04).
王选康,胡学昱,王哲.星形胶质细胞在脊髓损伤中作用的研究进展[J].中国脊柱脊髓杂志,2020(08).
Jie Chen,Xian-Ju Zhou,Rong-Bin Sun.Effect of the combination of high-frequency repetitive magnetic stimulation and neurotropin on injured sciatic nerve regeneration in rats[J].Neural Regeneration Research,2020(01).
宋志明,安恒远,张华,李鹏.骶神经根功能性磁刺激对脊髓损伤后神经源性膀胱过度活动症的作用[J].中国脊柱脊髓杂志,2019(06).
邓皓月,袁昌艳,王树琼,彭秋怡,舒彬.磁刺激初级运动皮层(M1区)对不完全性脊髓损伤患者膀胱功能的影响[J].重庆医科大学学报,2020(01).
吴勤峰,施加加,李向哲,郑洁,顾丽萍,徐小俊,魏天祺,王彤.重复经颅磁刺激治疗外伤性脊髓损伤后神经病理性疼痛的疗效观察[J].中国康复医学杂志,2018(03).
董璐洁,于利国,陈沫,刘雅丽.重复经颅磁刺激对不完全性脊髓损伤患者痉挛的影响[J].中国康复,2017(04).
琚芬,王冰水,牟翔,袁华,赵晨光.重复经颅磁刺激对脊髓损伤后神经性疼痛及大脑皮质兴奋性的影响[J].中国康复医学杂志,2017(05).
王艺,周贤丽,侯岷,张秀莉,尚超平,吴宗耀.磁刺激对脊髓损伤后运动功能障碍的疗效观察[J].中国康复,2016(04).
韩晓阁,杨晓秋.重复经颅磁刺激治疗神经病理性疼痛研究进展[J].中国康复理论与实践,2016(07).
Stéphane Vinit,Michel Petitjean.Novel role for transcranial magnetic stimulation to study post-traumatic respiratory neuroplasticity[J].Neural Regeneration Research,2016(07).
Jin-lan Jiang,Xu-dong Guo,Shu-quan Zhang,Xin-gang Wang,Shi-feng Wu.Repetitive magnetic stimulation affects the microenvironment of nerve regeneration and evoked potentials after spinal cord injury[J].Neural Regeneration Research,2016(05).
潘钰,汪璇,刘萍,陈赞,王玉兰.经颅和经脊髓重复磁刺激对脊髓半横断大鼠运动功能的作用[J].中国康复理论与实践,2013(04).
He Wei,Li Zhi qiang,Gu Hou yun,Pan Qi lin,Lin Fei xiang.Targeted Therapy of Spinal Cord Injury: Inhibition of Apoptosis Is a Promising Therapeutic Strategy[J].Molecular Neurobiology,2023(7).
Clifford Tanner,Finkel Zachary,Rodriguez Brianna,Joseph Adelina,Cai Li.Current Advancements in Spinal Cord Injury Research—Glial Scar Formation and Neural Regeneration[J].Cells,2023.
Xiao Chun-Lin,Yin Wen-Chao,Zhong Yan-Chun,Luo Jia-Quan,Liu Lu-Lin,Liu Wu-Yang,Zhao Kai.The role of PI3K/Akt signalling pathway in spinal cord injury[J].Biomedicine & Pharmacotherapy,2022.
Fan Jin,Fu Hui,Xie Xiaolong,Zhong Dongling,Li Yuxi,Liu Xiaobo,Zhang Huiling,Zhang Jun,Huang Jiaxi,Li Juan,Jin Rongjiang,Zheng Zhong.The effectiveness and safety of repetitive transcranial magnetic stimulation on spasticity after upper motor neuron injury: A systematic review and meta-analysis[J].Frontiers in Neural Circuits,2022.
Perez Nathalie Elisabeth,Godbole Neha Pradyumna,Amin Katherine,Syan Raveen,Gater David R..Neurogenic Bladder Physiology, Pathogenesis, and Management after Spinal Cord Injury[J].Journal of Personalized Medicine,2022.
Huang Maomao,Luo Xi,Zhang Chi,Xie YuJie,Wang Li,Wan Tenggang,Chen Ruyan,Xu Fangyuan,Wang JianXiong.Effects of repeated transcranial magnetic stimulation in the dorsolateral prefrontal cortex versus motor cortex in patients with neuropathic pain after spinal cord injury: a study protocol.[J].BMJ open,2022.
Saleh Christian,Ilia Tatiani Soultana,Jaszczuk Phillip,HundGeorgiadis Margret,Walter Anna.Is transcranial magnetic stimulation as treatment for neuropathic pain in patients with spinal cord injury efficient? A systematic review.[J].Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology,2022.
Lee KunZe,Liou LiMin,Vinit Stéphane,Ren MingYue.Rostral-caudal effect of cervical magnetic stimulation on the diaphragm motor evoked potential following cervical spinal cord contusion in the rat.[J].Journal of neurotrauma,2021.
Robac Amandine,Neveu Pauline,Hugede Alizée,Garrido Elisabeth,Nicol Lionel,Delarue Quentin,Guérout Nicolas.Repetitive Trans Spinal Magnetic Stimulation Improves Functional Recovery and Tissue Repair in Contusive and Penetrating Spinal Cord Injury Models in Rats[J].Biomedicines,2021.
Hou Yonghui,Luan Jiyao,Huang Taida,Deng Tiancheng,Li Xing,Xiao Zhifeng,Zhan Jiheng,Luo Dan,Hou Yu,Xu Liangliang,Lin Dingkun.Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response[J].Journal of Neuroinflammation,2021.
Krogh Søren,Aagaard Per,Jønsson Anette Bach,Figlewski Krystian,Kasch Helge.Effects of repetitive transcranial magnetic stimulation on recovery in lower limb muscle strength and gait function following spinal cord injury: a randomized controlled trial.[J].Spinal cord,2021.
Liang Hui,Xu Congjie,Hu Shijun,Wen Gang,Lin Jie,Liu Tao,Xu Jiyi.Repetitive Transcranial Magnetic Stimulation Improves Neuropathy and Oxidative Stress Levels in Rats with Experimental Cerebral Infarction through the Nrf2 Signaling Pathway[J].Evidence-Based Complementary and Alternative Medicine,2021.
Amanda Phuong Tran,Philippa Mary Warren,Jerry Silver.New insights into glial scar formation after spinal cord injury[J].Cell and Tissue Research,2021.
Delarue Quentin,Robac Amandine,Massardier Romane,Marie JeanPaul,Guérout Nicolas.Comparison of the effects of two therapeutic strategies based on olfactory ensheathing cell transplantation and repetitive magnetic stimulation after spinal cord injury in female mice.[J].Journal of neuroscience research,2021.
Marufa Siti Ainun,Hsieh TsungHsun,Liou JianChiun,Chen HsinYung,Peng ChihWei.Neuromodulatory effects of repetitive transcranial magnetic stimulation on neural plasticity and motor functions in rats with an incomplete spinal cord injury: A preliminary study.[J].PloS one,2021.
Liu Hao,Xiong Deqi,Pang Rizhao,Deng Qian,Sun Nianyi,Zheng Jinqi,Liu Jiancheng,Xiang Wu,Chen Zhesi,Lu Jiachun,Wang Wenchun,Zhang Anren.Effects of repetitive magnetic stimulation on motor function and GAP43 and 5-HT expression in rats with spinal cord injury[J].Journal of International Medical Research,2020.
Anjum Anam,Yazid Muhammad Da’in,Fauzi Daud Muhammad,Idris Jalilah,Ng Angela Min Hwei,Selvi Naicker Amaramalar,Ismail Ohnmar Htwe@ Rashidah,Athi Kumar Ramesh Kumar,Lokanathan Yogeswaran.Spinal Cord Injury: Pathophysiology, Multimolecular Interactions, and Underlying Recovery Mechanisms[J].International Journal of Molecular Sciences,2020.
Chalfouh C,Guillou C,Hardouin J,Delarue Q,Li X,Duclos C,Schapman D,Marie J P,Cosette P,Guérout N.The Regenerative Effect of Trans-spinal Magnetic Stimulation After Spinal Cord Injury: Mechanisms and Pathways Underlying the Effect.[J].Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics,2020.
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Department of Urology, China Rehabilitation Research Center, Beijing, China.,Department of Urology, Capital Medical University, Beijing, China.,Department of Urology, China Rehabilitation Research Center, Beijing, China.,Department of Urology, Capital Medical University, Beijing, China.,Department of Urology, China Rehabilitation Research Center, Beijing, China.,Department of Urology, Capital Medical University, Beijing, China.,Department of Urology, China Rehabilitation Research Center, Beijing, China.,Department of Urology, Capital Medical University, Beijing, China..Urodynamic findings during the filling phase in neurogenic bladder patients with or without vesicoureteral reflux who have undergone sacral neuromodulation.[J].Neurourology and urodynamics,2020.
Hutson Thomas H,Di Giovanni Simone.The translational landscape in spinal cord injury: focus on neuroplasticity and regeneration.[J].Nature reviews. Neurology,2019.
Tracey L. Wheeler,William de Groat,Kymberly Eisner,Anton Emmanuel,Jennifer French,Warren Grill,Michael J. Kennelly,Andrei Krassioukov,Bruno Gallo Santacruz,Fin Biering-Sørensen,Naomi Kleitman.Translating promising strategies for bowel and bladder management in spinal cord injury[J].Experimental Neurology,2018.
Romo Paholo G Barboglio,Smith Christopher P,Cox Ashley,Averbeck Márcio A,Dowling Caroline,Beckford Cleveland,Manohar Paul,Duran Sergio,Cameron Anne P.Non-surgical urologic management of neurogenic bladder after spinal cord injury.[J].World journal of urology,2018.
Carolina Rouanet,Danyelle Reges,Eva Rocha,Vivian Gagliardi,Gisele Sampaio Silva.Traumatic spinal cord injury: current concepts and treatment update[J].Arquivos de Neuro-Psiquiatria,2017.
Joshua Hendrikse,Aaron Kandola,James Coxon,Nigel Rogasch,Murat Yücel.Combining aerobic exercise and repetitive transcranial magnetic stimulation to improve brain function in health and disease[J].Neuroscience and Biobehavioral Reviews,2017.
Jose A Corleto,Mariana Bravo-Hernández,Kota Kamizato,Osamu Kakinohana,Camila Santucci,Michael R Navarro,Oleksandr Platoshyn,Dasa Cizkova,Nadezda Lukacova,Julian Taylor,Martin Marsala.Thoracic 9 Spinal Transection-Induced Model of Muscle Spasticity in the Rat: A Systematic Electrophysiological and Histopathological Characterization.[J].PLoS ONE,2017.
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Raffaele Nardone,Patrick B. Langthaler,Andrea Orioli,Peter Höller,Yvonne Höller,Vanessa N. Frey,Francesco Brigo,Eugen Trinka.Effects of intermittent theta burst stimulation on spasticity after spinal cord injury[J].Restorative Neurology and Neuroscience,2017.
Ahuja Christopher S,Nori Satoshi,Tetreault Lindsay,Wilson Jefferson,Kwon Brian,Harrop James,Choi David,Fehlings Michael G.Traumatic Spinal Cord Injury-Repair and Regeneration.[J].Neurosurgery,2017.
Hatice Kumru,Jesus Benito-Penalva,Josep Valls-Sole,Narda Murillo,Josep M. Tormos,Cecilia Flores,Joan Vidal.Placebo-controlled study of rTMS combined with Lokomat ® gait training for treatment in subjects with motor incomplete spinal cord injury.[J ] .Experimental brain research,2016.
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Xiaoming Zhang,Ela Plow,Vinoth Ranganthan,Honglian Huang,Melissa Schmitt,Gregory Nemunaitis,Clay Kelly,Frederick Frost,Vernon Lin.Functional Magnetic Stimulation of Inspiratory and Expiratory Muscles in Subjects With Tetraplegia[J].PM&R,2016.
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Leydeker Michael,Delva Stanley,Tserlyuk Igor,Yau Joseph,Wagdy Mekhael,Hawash Ahmed,Bendaoud Salim,Mohamed Salah,Wieraszko Andrzej,Ahmed Zaghloul.The effects of 15 Hz trans-spinal magnetic stimulation on locomotor control in mice with chronic contusive spinal cord injury.[J].Electromagnetic biology and medicine,2013.
Setsu Nakatani-Enomoto,Ritstuko Hanajima,Masashi Hamada,Yasuo Terao,Hideyuki Matsumoto,Yuichiro Shirota,Shingo Okabe,Masaki Hirose,Koichiro Nakamura,Toshiaki Furubayashi,Shunsuke Kobayashi,Hitoshi Mochizuki,Hiroyuki Enomoto,Yoshikazu Ugawa.Bidirectional modulation of sensory cortical excitability by quadripulse transcranial magnetic stimulation (QPS) in humans[J].Clinical Neurophysiology,2012.
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