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1. 郑州大学第一附属医院康复医学科,郑州
2. 郑州大学公共卫生学院,郑州
3. 乌海市蒙医中医医院康复中心,乌海
4. 四平一正中医医院康复医学科
5. 信阳市中心医院康复医学科,信阳
6. 国家卫生健康委脑血管病防治重点实验室(共建),郑州
Published:2024
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王甜梦, 曾泓辑, 李彩霞, et al. 脑卒中后吞咽障碍患者吸入性肺炎的影响因素分析及预测模型构建[J]. 2024, 46(7): 618-623.
目的分析脑卒中后吞咽障碍患者发生吸入性肺炎(AP)的影响因素并构建预测模型。方法采用回顾性调查方法
共纳入符合标准的脑卒中后吞咽障碍患者148例
根据住院期间是否发生AP将其分为AP组和非AP组
收集入选患者的一般人口学信息、临床资料等进行单因素分析和多因素Logistic回归分析
并构建列线图模型
同时采用受试者工作特征(ROC)曲线分析各相关因素及列线图模型对AP的预测价值。结果 AP组共有患者46例
非AP组共有患者102例
AP发生率为31.08%;通过多因素Logistic回归分析发现
年龄、Barthel指数评分、洼田饮水试验评级、营养支持方式、中性粒细胞/淋巴细胞比值(NLR)是脑卒中后吞咽障碍患者发生AP的重要影响因素(P<0.05);通过分析ROC曲线发现
年龄、洼田饮水试验评级、营养支持方式、NLR、Barthel指数评分及列线图模型预测AP的曲线下面积(AUC)分别为0.598、0.651、0.676、0.723、0.775、0.902
上述指标预测AP的灵敏度及特异度分别为91.30%和31.40%、97.80%和32.40%、78.30%和56.90%、67.40%和71.60%、82.60%和61.80%、84.80%和80.40%。结论年龄、洼田饮水试验评级、营养支持方式、NLR、Barthel指数评分均是影响脑卒中后吞咽障碍患者发生AP的重要因素
采用列线图模型预测AP的能力显著优于上述各因素单独预测。
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Chang Min Cheol,Choo Yoo Jin,Seo Kyung Cheon,Yang Seoyon.The Relationship Between Dysphagia and Pneumonia in Acute Stroke Patients: A Systematic Review and Meta-Analysis[J].Frontiers in Neurology,2022.
Yang Seoyon,Choo Yoo Jin,Chang Min Cheol.The Preventive Effect of Dysphagia Screening on Pneumonia in Acute Stroke Patients: A Systematic Review and Meta-Analysis[J].Healthcare,2021.
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Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, 48149 Muenster, Germany.,Institute for Biomagnetism and Biosignalanalysis, University of Muenster, 48149 Muenster, Germany.,Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, 48149 Muenster, Germany.,Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, 48149 Muenster, Germany.,Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, 48149 Muenster, Germany.,Institute for Biomagnetism and Biosignalanalysis, University of Muenster, 48149 Muenster, Germany.,Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, 48149 Muenster, Germany.,Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, 48149 Muenster, Germany.,Institute for Biomagnetism and Biosignalanalysis, University of Muenster, 48149 Muenster, Germany.,Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, 48149 Muenster, Germany.,Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, 48149 Muenster, Germany.,Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, 48149 Muenster, Germany.,Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, 48149 Muenster, Germany..The Impact of Dysphagia in Myositis: A Systematic Review and Meta-Analysis[J].Journal of Clinical Medicine,2020.
Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.,Shanghai Medical Center of Kidney, Shanghai, China.,Shanghai Institute of Kidney and Dialysis, Shanghai, China.,Shanghai Key Laboratory of Kidney and Blood Purification, Shanghai, China.,Hemodialysis Quality Control Center of Shanghai, Shanghai, China.,Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.,Shanghai Medical Center of Kidney, Shanghai, China.,Shanghai Institute of Kidney and Dialysis, Shanghai, China.,Shanghai Key Laboratory of Kidney and Blood Purification, Shanghai, China.,Hemodialysis Quality Control Center of Shanghai, Shanghai, China.,Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.,Shanghai Medical Center of Kidney, Shanghai, China.,Shanghai Institute of Kidney and Dialysis, Shanghai, China.,Shanghai Key Laboratory of Kidney and Blood Purification, Shanghai, China.,Hemodialysis Quality Control Center of Shanghai, Shanghai, China.,Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.,Shanghai Medical Center of Kidney, Shanghai, China.,Shanghai Institute of Kidney and Dialysis, Shanghai, China.,Shanghai Key Laboratory of Kidney and Blood Purification, Shanghai, China.,Hemodialysis Quality Control Center of Shanghai, Shanghai, China.,Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.,Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.,Shanghai Medical Center of Kidney, Shanghai, China.,Shanghai Institute of Kidney and Dialysis, Shanghai, China.,Shanghai Key Laboratory of Kidney and Blood Purification, Shanghai, China.,Hemodialysis Quality Control Center of Shanghai, Shanghai, China.,Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.,Shanghai Medical Center of Kidney, Shanghai, China.,Shanghai Institute of Kidney and Dialysis, Shanghai, China.,Shanghai Key Laboratory of Kidney and Blood Purification, Shanghai, China.,Hemodialysis Quality Control Center of Shanghai, Shanghai, China.,Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China, xiang.fangfang@zs-hospital.sh.cn.,Shanghai Medical Center of Kidney, Shanghai, China, xiang.fangfang@zs-hospital.sh.cn.,Shanghai Institute of Kidney and Dialysis, Shanghai, China, xiang.fangfang@zs-hospital.sh.cn.,Shanghai Key Laboratory of Kidney and Blood Purification, Shanghai, China, xiang.fangfang@zs-hospital.sh.cn.,Hemodialysis Quality Control Center of Shanghai, Shanghai, China, xiang.fangfang@zs-hospital.sh.cn.,Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.,Shanghai Medical Center of Kidney, Shanghai, China.,Shanghai Institute of Kidney and Dialysis, Shanghai, China.,Shanghai Key Laboratory of Kidney and Blood Purification, Shanghai, China.,Hemodialysis Quality Control Center of Shanghai, Shanghai, China..The Predictive Value of NT-Pro-Brain Natriuretic Peptide for Risk of Pneumonia in Patients on Maintenance Hemodialysis.[J].Blood purification,2020.
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